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Stereoselective pharmacokinetics of chlorpheniramine and the effect of ranitidine

โœ Scribed by Kevin M. Koch; Robin L. O'Connor-Semmes; Ian M. Davis; Yin Yin

Book ID
109389036
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
48 KB
Volume
87
Category
Article
ISSN
0022-3549

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The disposition of chlorpheniramine was examined in seven children, 6-14 years of age, following a O.l-mg/kg iv dose. Postinjection serum chlorpheniramine levels in each subject declined biexponentially, with the greatest intersubject variability occurring in the initial distribution of the drug. Th