๐”– Bobbio Scriptorium
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The effects of ranitidine and cimetidine on the pharmacokinetics and pharmacodynamics of metoprolol

โœ Scribed by M. C. CHELLINGSWORTH; S. LAUGHER; S. AKHLAGHI; D. B. JACK; M. J. KENDALL

Book ID
108602829
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
376 KB
Volume
2
Category
Article
ISSN
0269-2813

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Effect of concomitant administration of
Effect of concomitant administration of cimetidine and ranitidine on the pharmacokinetics and electrocardiographic effects of terfenadine
โœ P. K. Honig; D. C. Wortham; K. Zamani; D. P. Conner; J. C. Mullin; L. R. Cantile ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 628 KB

Terfenadine is a widely prescribed non-sedating antihistamine which undergoes rapid and almost complete first pass biotransformation to an active carboxylic acid metabolite. It is unusual to find unmetabolised terfenadine in the plasma of patients taking the drug. Terfenadine in vitro is a potent bl