๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Stereoselective pharmacokinetics of 3,4-methylenedioxymethamphetamine in the rat

โœ Scribed by Robert L. Fitzgerald; Robert V. Blanke; Alphonse Poklis


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
563 KB
Volume
2
Category
Article
ISSN
0899-0042

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Fluoxetine pretreatment effects pharmaco
โœ Vijay V. Upreti; Natalie D. Eddington ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 342 KB

Fluoxetine has been shown to provide protection from MDMA induced long term neurotoxicity. The purpose of this investigation is to evaluate the pharmacokinetic drug interaction between MDMA and fluoxetine and also to determine the role of P-glycoprotein (P-gp) on mediating drug-drug interactions wit

Stereoselective pharmacokinetics of flob
โœ Frantisek Trejtnar; Vladimir Wsol; Barbora Szotakova; Lenka Skalova; Petr Pavek; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 101 KB ๐Ÿ‘ 2 views

Stereoselectivity of the pharmacokinetics of the nonsteroidal antiinflammatory drug flobufen, 4-(2ะˆ,4ะˆ-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid, was studied in male Wistar rats after intravenous administration. Pharmacokinetic parameters and chiral inversion of flobufen enantiomers were st

Examination of the action of 3,4-methyle
โœ Andrew N. Gifford; Yoshio Minabe; Alon Toor; Rex Y. Wang; Charles R. Ashby Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 655 KB

Extracellular single cell recording was used to examine the effect of intravenous administration of ( -), (+), and ( 2 )-3,4-methylenedioxymethamphetamine (MDMA) on A10 dopamine (DA) neurons in chloral hydrate anesthetized male rats. Both (5)-MDMA and (+)-MDMA inhibited the firing rate of most (79%)

Effects of antihistamines on 3,4-methyle
โœ S.Y. Yeh; C. Dersch; R. Rothman; J.L. Cadet ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 254 KB ๐Ÿ‘ 2 views

This study investigated the effects of chlorpheniramine (CPA, 10-25 mg/kg), diphenhydramine (DIPH, 20 mg/kg), tripelennamine (TRIP, 20 mg/kg), and pyrilamine (PYRI, 20 mg/kg) on 3,4-methylenedioxymethamphetamine (MDMA, 20 mg/kg ฯซ 2)-induced hyperthermia and depletion of indoles in rat brains, on the

Pharmacokinetics of halofantrine in the
โœ Dion R. Brocks; Jason W. Toni ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB ๐Ÿ‘ 2 views

The antimalarial drug, halofantrine, is chiral and is administered clinically as the racemate. In order to define the pharmacokinetic properties of halofantrine enantiomers in the rat, male Sprague-Dawley rats (264-311 g) were given halofantrine HCl orally (n = 5; 14 mg/kg) or intravenously (i.v.) (