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Stereoselective peterson alkoxycarbonylmethylenation reaction of substituted cyclohexanones

✍ Scribed by Lucjan Strekowski; Melean Visnick; Merle A. Battiste


Book ID
104242580
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
187 KB
Volume
25
Category
Article
ISSN
0040-4039

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✦ Synopsis


Sunmary: In contrast to previous results the Peterson olefination reaction of substituted cyclohexanones with metallotrimethylsilylacetates (1) affords moderate to high stereoselectivity.


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Electrolysis of 4-substituted cyclohexanones in methanol in the presence of sodium halides in an undivided cell results in the stereoselective formation of cis-5-substituted-2,2-dimethoxycyclohexanols in 70-80% yield.