Stereoselective opening of chiral α-stannylacetals with organometallic reagents
✍ Scribed by Jean-Luc Parrain; Jean-Christophe Cintrat; Jean-Paul Quintard
- Book ID
- 107812288
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 239 KB
- Volume
- 437
- Category
- Article
- ISSN
- 0022-328X
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## Abstract α‐Methylbenzyllithium (6) should possess either central or planar chirality. The rate of enantiomerization of 6 at — 78^°^C was found to be faster than its addition to the amide 7, the ketone 8, or to the aldehyde 10, according to a test based on kinetic resolution. The benzyllithium co
Asymmetric Addition of Organometallic Reagents to Chiral α-Alkoxy Hydrazones. -The diastereoselective addition of three different types of nucleophilic reagents to three different α-alkoxy hydrazones is studied. With exception of the reation of the silylated hydrazone (Ib) with the heterogeneous 1: