Stereoselective Lewis Acid Mediated (3+2) Cycloadditions of N -H- and N -Sulfonylaziridines with Heterocumulenes
β Scribed by Craig, Robert A.; O'Connor, Nicholas R.; Goldberg, Alexander F. G.; Stoltz, Brian M.
- Book ID
- 126886347
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 586 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0947-6539
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π SIMILAR VOLUMES
BF 3 β’OEt 2 -mediated [3+2] cycloaddition of allyltriisopropylsilane to N-sulfonyl aldimine afforded silyl substituted pyrrolidines in good yields. Excellent cis selectivity was observed with aromatic aldimines.
## Dedicated to Professor Zhengming Li Cycloaddition is one of the most powerful tools for the construction of carbo-and heterocyclic skeletons, due to its high efficiency and atom economy. [1] Methylenecyclopropanes (MCPs) are useful building blocks in organic synthesis because they are readily a