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Stereoselective labelling of racemic oxazepam acetate and its use in studying stereoselective binding to human serum albumin

✍ Scribed by Simonyi, Mikl�s; Fitos, Ilona; Tegyey, Zsuzsanna


Book ID
126646738
Publisher
The Royal Society of Chemistry
Year
1980
Tongue
English
Weight
258 KB
Volume
23
Category
Article
ISSN
0022-4936

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Binding of ibuprofen (IB) enantiomers to human serum albumin (HSA) was studied using a chiral fluorescent derivatizing reagent, which enabled the measurement of IB enantiomers at a concentration as low 5 x 10(-8) M. Scatchard analyses revealed that there were two classes of binding sites for both en