𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereoselective kinetics of warfarin binding to human serum albumin: Effect of an allosteric interaction

✍ Scribed by Ilona Fitos; Júlia Visy; Julianna Kardos


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
106 KB
Volume
14
Category
Article
ISSN
0899-0042

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Stereoselective binding of carbenicillin
✍ Tomoo Itoh; Katashi Nakashima; Yasuyuki Tsuda; Hideo Yamada 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 602 KB

Binding of carbenicillin (CBPC) epimers to human serum albumin (HSA) was found to be stereoselective. Epimer-epimer interaction was also observed in the bmding to HSA. There were at least three binding sites on HSA for CBPC epimers, one of which (stereoselective site) was more in favor of S-CBPC tha

Stereoselectivity and enantiomer-enantio
✍ Tomoo Itoh; Yoshikazu Saura; Yasuyuki Tsuda; Hideo Yamada 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 2 views

Binding of ibuprofen (IB) enantiomers to human serum albumin (HSA) was studied using a chiral fluorescent derivatizing reagent, which enabled the measurement of IB enantiomers at a concentration as low 5 x 10(-8) M. Scatchard analyses revealed that there were two classes of binding sites for both en

Binding of anti-Parkinson's disease drug
✍ Gabriella Fanali; Viviana Rampoldi; Alessandra di Masi; Alessandro Bolli; Leonar 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB

Binding of drugs to plasma proteins is an important determinant for their efficacy because it modulates drug availability to the intended target. Co-administered drugs may bind to the same protein site or to different functionally linked clefts following competitive and allosteric mechanisms. Here,