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Stereoselective Inhibition of Cholesterol Esterase by Enantiomers ofexo- andendo-2-Norbornyl-N–n-butylcarbamates

✍ Scribed by Ming-Cheng Lin; Shyh-Jei Yeh; I-Ru Chen; Gialih Lin

Book ID: 106424003
Publisher: Springer
Year: 2011
Tongue: English
Weight: 428 KB
Volume: 30
Category: Article
ISSN: 1573-4943
DOI: 10.1007/s10930-011-9323-3

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## Abstract Enantiomers of __cis__,__cis__‐decahydro‐2‐naphthyl‐N‐__n__‐butylcarbamate show stereo‐specific inhibition for acetylcholinesterase and butyrylcholinesterase. For both inhibition reaction, (2__S__,4a__R__,8a__S__)‐__cis__,__cis__‐decahydro‐2‐naphthyl‐N‐__n__‐ butylcarbamate is more pote