A chiral HPLC method has been developed to separate razoxane (ICRF-159) in blood plasma into its enantiomers dexrazoxane (ICRF-187) and levrazoxane (ICRF-186). Dexrazoxane is clinically used as a doxorubicin cardioprotective agent and little is known of its in vivo metabolism. After intravenous admi
β¦ LIBER β¦
Stereoselective hydrolysis of ICRF-187 (dexrazoxane) and ICRF-186 by dihydropyrimidine amidohydrolase
β Scribed by Dr. Brian B. Hasinoff
- Book ID
- 102077650
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 332 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
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