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Stereoselective hydrogenation of (2S,5R)-(−)-menthone in presence of β-cyclodextrin

✍ Scribed by R. Ravichandran


Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
137 KB
Volume
256
Category
Article
ISSN
1381-1169

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First stereoselective synthesis of (1S,2
✍ Henrichfreise, Peter ;Scharf, Hans-Dieter 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 510 KB

## Abstract Starting from 2,3‐__O__‐(3‐pentylidene)‐D‐glyceraldehyde (3), we prepared the bicyclic pheromone (1__S__,2__S__,4__R__,5__R__)‐(−)‐β‐multistriatin (1) on a gram scale. Key steps of the synthesis are a __cis__‐selective Wittig olefination followed by diastereo‐selective Michael addition