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Stereoselective glutathione conjugation of a uricosuric diuretic

✍ Scribed by Junko Higaki; Masaharu Hirata


Book ID
113137193
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
263 KB
Volume
72
Category
Article
ISSN
0009-2797

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Stereoselective pharmacokinetics of a no
✍ Kazutaka Higaki; Kyoko Kadono; Masayuki Nakano πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 601 KB

5-Dimethylsulfamoyl-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxyli c acid (DBCA), a promising uricosuric, diuretic, and antihypertensive agent, was administered intravenously to rats. The levels of DBCA in plasma and the areas under the curve of concentration versus time (AUC values) of the S(-)-ena