Stereoselective Functionalization of the 1‘-Position of 4‘-Thionucleosides
✍ Scribed by Gunaga, Prashantha; Kim, Hea Ok; Lee, Hyuk Woo; Tosh, Dilip K.; Ryu, Jae-Sang; Choi, Sun; Jeong, Lak Shin
- Book ID
- 120445028
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 81 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1523-7060
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Convenient one-pot procedures using iodine monochloride have been developed for the preparation of two 4thio-1,2-glycals from readily available starting materials and for their β-anomer selective conversion into 2 -iodo-4 -thionucleosides. Conditions for the reductive de-iodination of these iodonucl