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Stereoselective first total synthesis, confirmation of the absolute configuration and bioevaluation of botryolide-E

✍ Scribed by D. Kumar Reddy; V. Shekhar; P. Prabhakar; D. Chanti Babu; D. Ramesh; B. Siddhardha; U.S.N. Murthy; Y. Venkateswarlu


Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
271 KB
Volume
21
Category
Article
ISSN
0960-894X

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Total Synthesis of (–)-Isopisiferin: Con
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## Abstract Starting from 4,4‐dimethyl‐2‐cyclohexenone, an enantioselective synthesis of (–)‐isopisiferin has been accomplished in 15 steps with an overall yield of 11.4 %. This work not only provides synthetic evidence for confirming the absolute configuration of natural isopisiferin itself, but a