𝔖 Bobbio Scriptorium
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Stereoselective Enzymatic Esterification of 3-BenzoyIthio-2-methylpropanoic Acid

✍ Scribed by RAMESH N. PATEL; JEFFREY M. HOWELL; AMIT BANERJEE; KENNETH F. FORTNEY; LASZLO J. SZARKA


Book ID
119867705
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
416 KB
Volume
672
Category
Article
ISSN
0890-6564

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A key intermediate, S-(-)-3-benzoylthio-2methylpropanoic acid ( 1 ) w a s made in high optical purity by the lipase-catalyzed stereoselective esterification of racemic 1 with methanol in an organic solvent system. Among various lipases evaluated, Amano P-30 lipase from Pseudomonas sp. efficiently ca

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## Abstract Formal CH~2~ insertion in bioconjugates composed of 1′‐aminoferrocene‐1‐carboxylic acid (Fca) and alanine Boc‐Ala‐Fca‐Ala‐OCH~3~ gives Fca bioconjugates with the β‐amino acid (__S__)‐3‐amino‐2‐methylpropanoic acid (Aib). The novel homologous conjugates of ferrocene were fully characteri