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Stereoselective distribution and stereoconversion of zopiclone enantiomers in plasma and brain tissues in rats

✍ Scribed by Christine Fernandez; Patrice Alet; Catherine Davrinche; Joelle Adrien; Alain Thuillier; Robert Farinotti; François Gimenez

Book ID
111768908
Publisher
Pharmaceutical Press
Year
2002
Tongue
English
Weight
190 KB
Volume
54
Category
Article
ISSN
2042-7158

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Stereoselective plasma protein binding and target tissue distribution of clausenamide enantiomers in rats
✍ Chuan Jiang Zhu; Jun Tian Zhang 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 2 views

Stereoselective differences in pharmacokinetics between clausenamide (CLA) enantiomers have been found after intravenous and oral administration of each enantiomer to rats. The differences could be associated with protein binding of CLA enantiomers. By equilibrium dialysis methods, the binding of CL