We recently reported the first examples of conjugate additions of alkyl sulphoxides to unsaturated esters,\* These reactions proceed with good selectivity and provide a promising new method for carrying out
Stereoselective conjugate additions of sulphoxide stabilised carbanions to α,β-unsaturated esters
✍ Scribed by M. Casey; A.C. Manage; L. Nezhat
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 266 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Summaqv: The reaction of Iithiated a&l t-butyl sulphoxides with a&unsaturated esters gives conjugate addition products in good yield, with high stereoselectivity.
Asymmetric conjugate additions to a&unsaturated carbonyl compounds have been the subject of (
📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
The effective conjugate addition of a dimethyl phosphonate moiety to a&unsaturated esters and kefones is described. This addition is promoted specifically by trimethylaluminum and does not occur with other Lewis acids which have been examined to date.