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Stereoselective Alkylation of Chiral 2-Imidoylphenols with Organolithium Reagents: Synthesis of Enantiopure 2-Aminoalkylphenols

✍ Scribed by Cimarelli, Cristina; Palmieri, Gianni; Volpini, Emanuela


Book ID
120580273
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
134 KB
Volume
68
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Direct Alkylation o
✍ H. NAKAMURA; M. AIZAWA; A. MURAI πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 27 KB πŸ‘ 1 views

Direct Alkylation of 2-Acylamino-and 2-Aminopyrazines with Organolithium Reagents. -Regioselective alkylation of 2-Aminopyrazine at the 3-position is achieved with organolithium reagents in THF at low temperature. The preparation of (IIId) represents a formal total synthesis of coelenterazine.