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Stereoselective Aldol-Type Cyclization Reaction Mediated by Dibutylboron Triflate/Diisopropylethylamine

โœ Scribed by Das, Sanjib; Li, Lian-Sheng; Sinha, Subhash C.


Book ID
120028441
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
213 KB
Volume
6
Category
Article
ISSN
1523-7060

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The divalent tin enol ether of the racemic N-BOC ot-aminodienone tricarbonyliron complex 4 reacts with both enantiomers of protected lactaldehydes to predominantly yield one optically active ketol diastereoisomer (45 %). From the enantiomerically pure complex (S).(+)-4 and (R)-(+) tert butyldimethyl