The reaction of tin enolates of cyclohexanone or propiophenone with benzaldehyde at -78'C gives predominately the threo aldol diastereomer.
Stereoselective aldol condensations of organotin reagents with aldehydes
โ Scribed by Sharada S. Labadie; J.K. Stille
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 777 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4020
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๐ SIMILAR VOLUMES
Anhydrous RuC13 catalyses the efficient cross aldol condensations of different ketones with various aromatic aldehydes in sealed tube under solvent free conditions without the occurrence of any self condensations. Regioselective self condensation reaction of some ketones and aldehydes are also desc
## Abstract For Abstract see ChemInform Abstract in Full Text.
A study on the addition of boron enolates of methyl ketones to trans a,b-epoxy aldehydes is reported. The reaction proceeds with an excellent anti stereoselectivity, consistent with the Felkin-Ahn model, toward the synthesis of hydroxylated compounds with defined stereochemistry.