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Stereoelectronic effects and the active site of the serine proteases

โœ Scribed by Huff, Jeffrey B.; Askew, Ben.; Duff, Robert J.; Rebek, Julius.

Book ID
127295476
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
273 KB
Volume
110
Category
Article
ISSN
0002-7863

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Calculation of kinetic constants of an enzymatic reaction in organic solvents requires knowledge of the functional active-site concentration in organic solvents, and this can be significantly different than that in water. An experimental method for active-site titration of serine proteases in organi