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Stereodivergent Addition of Allylmetal Reagents to Imines Derived from (R)-2,3-Di-O-benzylglyceraldehyde by Appropriate Selection of Metal and Double Stereodifferentiation.

✍ Scribed by Ramon Badorrey; Carlos Cativiela; Maria D. Diaz-de-Villegas; Roberto Diez; Jose A. Galvez


Publisher
John Wiley and Sons
Year
2003
Weight
158 KB
Volume
34
Category
Article
ISSN
0931-7597

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Stereodivergent Addition of Allylmetal R
✍ Ramón Badorrey; Carlos Cativiela; María D. Díaz-de-Villegas; Roberto Díez; José  📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

The addition of allylmetal reagents to N-benzylimines derived from (R)-2,3-di-O-benzylglyceraldehyde has been achieved with high yields and diastereoselectivities. Homoallylamine 2a of syn configuration is obtained preferentially with allylmagnesium bromide, whereas homoallylamine 2a of anti configu