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Addition of allylmetal reagents to the imine derived from 2-pyridine carboxaldehyde and methyl (S)-valinate. Synthesis of (S)- and (R)-1-(2-pyridyl)-3-butenamine

✍ Scribed by Giuseppe Alvaro; Diego Savoia


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
595 KB
Volume
7
Category
Article
ISSN
0957-4166

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Stereodivergent Addition of Allylmetal R
✍ Ramón Badorrey; Carlos Cativiela; María D. Díaz-de-Villegas; Roberto Díez; José  📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

The addition of allylmetal reagents to N-benzylimines derived from (R)-2,3-di-O-benzylglyceraldehyde has been achieved with high yields and diastereoselectivities. Homoallylamine 2a of syn configuration is obtained preferentially with allylmagnesium bromide, whereas homoallylamine 2a of anti configu