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Stereodifferentiation in a Chiral 1,4-Oxazin-2-one Derived from 2-Hydroxy-2-methyl-1-tetralone − A Reagent for Deracemization of Amino Acids

✍ Scribed by Arlette Solladié-Cavallo; Oldrich Sedy; Marta Salisova; Michel Schmitt


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
168 KB
Volume
2002
Category
Article
ISSN
1434-193X

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Asymmetric Synthesis Employing a Chiral
✍ Oliver Achatz; Andrea Grandl; Klaus Theodor Wanner 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB 👁 1 views

A new asymmetric synthesis of disubstituted α-amino acids From the major diastereomers 17c-d the corresponding αamino acids 19c-d are obtained enantiomerically pure upon is presented. This synthesis is based on the chiral 5-methoxy-1,4-oxazin-2-one derivative 5 relying on the α-hydroxy acid hydroly