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A Convenient Two-Step Synthesis of Amino Acid Derived Chiral 3-Substituted [1,4]Benzodiazepin-2-ones.

โœ Scribed by Jitendra Kumar Mishra; Gautam Panda


Publisher
John Wiley and Sons
Year
2005
Weight
22 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

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Benzodiazepin-1-one-2-carboxylic Acid and a 3-Cyanoindole. -Key step of the described synthesis is the intramolecular cyclization of the precursors (IV) and (VI) in Ph 2 O. In the latter case compound (VII), which is formed via elimination of HNCO, is isolated as a side product. -(