ChemInform Abstract: A Convenient Synthesis of 4,5-Benzodiazepin-1-one-2-carboxylic Acid and a 3-Cyanoindole.

✍ Scribed by A. PIPAUD; R. ROCHER; J. CHENAULT

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199735041

✦ Synopsis

Benzodiazepin-1-one-2-carboxylic Acid and a 3-Cyanoindole.

-Key step of the described synthesis is the intramolecular cyclization of the precursors (IV) and (VI) in Ph 2 O. In the latter case compound (VII), which is formed via elimination of HNCO, is isolated as a side product. -(