𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereocontrolled Total Synthesis of (−)-Kainic Acid. Regio- and Stereoselective Lithiation of Pyrrolidine Ring with the (+)-Sparteine Surrogate

✍ Scribed by Morita, Yasuhiro; Tokuyama, Hidetoshi; Fukuyama, Tohru


Book ID
125969301
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
103 KB
Volume
7
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Regio and stereochemically controlled ri
✍ J.R. Schauder; A. Krief 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 255 KB

This epoxide was obtained stereoselectively (> 95% ) on reaction of corresponding C-2O,C-22 olefin with osmium tetroxide (1.2 eq., 10°,1hr,85X yield) followed by basic cyclisation of the resulting C-2O,C-22 diol via its C-22 monomesylate (74% overall yield).