𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereocontrolled Synthesis of the Northern Part of Potent Proteasome Inhibitor TMC-95A

✍ Scribed by Inoue, Masayuki; Furuyama, Hidetomo; Sakazaki, Hayato; Hirama, Masahiro


Book ID
127347953
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
59 KB
Volume
3
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Enantioselective construction of the oxi
✍ Dawei Ma; Qingquan Wu πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 122 KB

The oxidized tryptophan analogue 5, a proposed intermediate for a synthesis of the proteasome inhibitors TMC-95A and TMC-95B, is prepared using the condensation of oxindole 7 with the (R)-Garner aldehyde and stereoselective dihydroxylation of olefin 6 as key steps.