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Stereocontrol in the reduction of 1,2-diimine with an oxazaborolidine catalyst. Highly stereoselective preparation of (R,R)-1,2-diphenylethylenediamine

โœ Scribed by Makoto Shimizu; Mie Kamei; Tamotsu Fujisawa


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
282 KB
Volume
36
Category
Article
ISSN
0040-4039

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The dependency of the enantioselectivity on the solvent and hydride source for the asymmetric reduction of acetophenone catalysed by the oxazaborolidine derived from cis-(1R,2S)-1-amino-indan-2-ol have been investigated. 11 B NMR studies have implied that monomer/dimer ratios are important for achie