Stereochemistry of the Kulinkovich Cyclopropanation of Nitriles
β Scribed by Astashko, Dmitry; Lee, Hyung Goo; Bobrov, Denis N.; Cha, Jin K.
- Book ID
- 120508774
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 786 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The stereochemical course of the intramolecular carbenoid cyclopropanation reaction has been studied for the epimeric carbenoids 12a and 12b. In these reactions the terl-butyldimethylsilyloxy substituent serves as an internal stereochemical reference point. It was found that 12b cyclizes rapidly at
Systematic evaluation of several titanium alkoxides and aryloxides was undertaken in the titanium-mediated cyclopropanation reactions of carboxylic esters. Chlorotitanium triisopropoxide and/or methyltitanium triisopropoxide were found to be the reagents of choice for the olefin exchange modificatio