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Stereochemistry of the Inhibition of δ-Chymotrypsin with Optically Active cis-Decaline-Type Organophosphates: 31P-NMR studies

✍ Scribed by Stefan Furegati; Walter Ganci; Georg Przibille; Peter Rüedi


Publisher
John Wiley and Sons
Year
1998
Tongue
German
Weight
699 KB
Volume
81
Category
Article
ISSN
0018-019X

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✦ Synopsis


For a full account on the background of the project, its context, and pertinent references, see [I]. ' ) '') This finding is different from those in similar experiments with the corresponding iruns-decaline-type phosphates la and Ib, where the inhibltors never exhibited signals, and significant resonances of reaction products could be detected only after cu. 1 -2 h [l].


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Synthesis of Enantiomerically Pure 1,5,5
✍ Markus J. Stöckli; Peter Rüedi 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 498 KB

## Abstract The irreversible inhibition of __δ__‐chymotrypsin with the enantiomerically pure, P(3)‐axially and P(3)‐equatorially X‐substituted __cis‐__ and __trans‐__configurated 2,4‐dioxa‐3‐phospha(1,5,5‐^2^H~3~)bicyclo[4.4.0]decane 3‐oxides (X=F, 2,4‐dinitrophenoxy) was monitored by ^31^P‐NMR spe