Stereochemistry of the Inhibition of δ-Chymotrypsin with Optically Active Bicyclic Organophosphates: 31P-NMR studies
✍ Scribed by Walter Ganci; Eric J. M. Meier; Franco A. Merckling; Georg Przibille; Urs Ringeisen; Peter Rüedi
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- German
- Weight
- 861 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0018-019X
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For a full account on the background of the project, its context, and pertinent references, see [I]. ' ) '') This finding is different from those in similar experiments with the corresponding iruns-decaline-type phosphates la and Ib, where the inhibltors never exhibited signals, and significant reso
## Abstract The irreversible inhibition of __δ__‐chymotrypsin with the enantiomerically pure, P(3)‐axially and P(3)‐equatorially X‐substituted __cis‐__ and __trans‐__configurated 2,4‐dioxa‐3‐phospha(1,5,5‐^2^H~3~)bicyclo[4.4.0]decane 3‐oxides (X=F, 2,4‐dinitrophenoxy) was monitored by ^31^P‐NMR spe