Stereochemistry of intramolecular cyclopropanation of an organoiron reagent
โ Scribed by Iyer, Ramnath S.; Kuo, Gee Hong; Helquist, Paul
- Book ID
- 127278672
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 412 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
The stereochemical course of the intramolecular carbenoid cyclopropanation reaction has been studied for the epimeric carbenoids 12a and 12b. In these reactions the terl-butyldimethylsilyloxy substituent serves as an internal stereochemical reference point. It was found that 12b cyclizes rapidly at
A ready intramolecular addition of the Grignard function of the 3,4-pentadien-l-y1 Grignard reagent (2) to an allenic double bond furnished the l-cyclopropylvinyl Grignard reagent (5). \* The structure of this new compound is consistent with its elemental analysis and ir and nmr spectra.