Stereochemistry of asymmetric silicon: Coupling reactions with organometallic reagents

✍ Scribed by L.H. Sommer; P.G. Rodewald; G.A. Parker

• Book ID: 104212222
• Publisher: Elsevier Science
• Year: 1962
• Tongue: French
• Weight: 160 KB
• Volume: 3
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)70527-2

✦ Synopsis

ONE of the most useful methods for establishing carbon-silicon bonds is the coupling reaction of organometallic reagents with silicon-halogen and silicon-alkoxy compounds. We wish to report new stereochemical data which bear on the problem of the mechanisms of these interesting reactions. These data relate to reactions of optically active o-naphthylphenylmethylsilanes,l a-NpPhMeSiY, designated R Si*Y 3 below.

Reaction of R3Si*OMe with ethylmagnesium bromide in ether is slow at