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Stereochemistry of 1,2-oxaphospholanes. Part X. Synthesis, X-ray structure and NMR spectroscopy of (2S*,3R*,5R*)-2-methoxy-3,5-dimethyl-2-oxo-1,2-oxaphospholan-3-ol

✍ Scribed by A. E. Wróblewski; W. T. Konieczko; J. Skoweranda; M. Bukowska-Strzyżewska


Book ID
111705466
Publisher
Springer
Year
1991
Tongue
English
Weight
439 KB
Volume
21
Category
Article
ISSN
1572-8854

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✍ Wróblewski, Andrzej E. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 511 KB

Addition of dimethyl phosphonate to acetaldol gives a 3 : 7 mixture of diastereomeric dimethyl (1,3-dihydroxybutyl)phosphonates 3 and 4. The relative configurations at C-I and C-3 in these diols were established by the 13C NMR data of their 0-benzylidene derivatives. Axial preference-for the dimetho