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Stereochemistry and mechanism of catalytic hydrogenation of substituted cyclohexanones

โœ Scribed by S. Mitsui; H. Saito; Y. Yamashita; M. Kaminaga; Y. Senda


Publisher
Elsevier Science
Year
1973
Tongue
French
Weight
629 KB
Volume
29
Category
Article
ISSN
0040-4020

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๐Ÿ“œ SIMILAR VOLUMES


Stereochemistry and mechanism of catalyt
โœ S. Mitsui; K. Gohke; H. Saito; A. Nanbu; Y. Senda ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 598 KB

Substituted alkyhnethylenecyclohexanes were hydrogenated over several transition metal catalysts. The ratios of the epimeric products were almost unity over freshly prepared Raney Ni but the axial Me counterparts were favoured over aged catalyst. The axial Me products were also preferred on Pt or Rh

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Enantioselective deprotonation of 4-substituted cyclohexanones (1) in the presence of excess trimethylsilyl chloride was examined using chirai bidentate lithium amides ((R)-3~(R)-7) in THF. The solution structures of (R)-3a in THF in the presence and in the absence of lithium chloride were studied b