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Stereochemically controlled synthesis of 1,8-dioxaspiro[4.5]decanes and 1-oxa-8-thiaspiro[4.5]decanes by phenylsulfanyl migration

โœ Scribed by Jason Eames; Maria A. de las Heras; Ray V.H. Jones; Stuart Warren


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
221 KB
Volume
37
Category
Article
ISSN
0040-4039

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The title compound, a 4-amino-4-arylcyclohexanone derivative with central analgesic activit was labeled with tritium at the C-7 and C-9 positions. Deuterium lakeled intermediates were used as models for developing isotope exchange and synthetic procedures. Deuterium and tritium labeled title compoun