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Stereochemical features of iodocyclisations of 3-alkene-1,2-diols to β-hydroxytetrahydrofurans

✍ Scribed by Sean P Bew; Jenny M Barks; David W Knight; Robert J Middleton

Book ID
104210362
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
134 KB
Volume
41
Category
Article
ISSN
0040-4039

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Iodoetherification of 4-penten-1,3-diols: stereoselective synthesis of cis 2-iodomethyl-3-hydroxytetrahydrofurans
✍ Yoshinao Tamaru; Shin-ichi Kawamura; Zen-ichi Yoshida 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 259 KB

cis 2-Iodomethyl-3-hydroxytetrahydrofurans have been obtained in high yields and in high selectivities by treatment of 4-penten-1.3-diols with iodine (ether-H20, NaHC03). Recently many methodologies have been developed for the stereocontrolled preparation of substituted tetrahydrofurans. 1 Here we d