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Stereochemical basis of DNA bending by transcription factors

✍ Scribed by Suzuki, Masashi; Yagi, Naoto


Book ID
115543100
Publisher
Oxford University Press
Year
1995
Tongue
English
Weight
802 KB
Volume
23
Category
Article
ISSN
0305-1048

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Bending of DNA by transcription factors
✍ Peter C. van der Vliet; C. Peter Verrijzer πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 805 KB

An increasing number of transcription factors both from prokaryotic and eukaryotic sources are found to bend the DNA upon binding to their recognition site. Bending can easily be detected by the anomalous electrophoretic behaviour of the DNA-protein complex or by increased cyclization of DNA fragmen