Bending of DNA by transcription factors
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Peter C. van der Vliet; C. Peter Verrijzer
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Article
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1993
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John Wiley and Sons
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English
β 805 KB
An increasing number of transcription factors both from prokaryotic and eukaryotic sources are found to bend the DNA upon binding to their recognition site. Bending can easily be detected by the anomalous electrophoretic behaviour of the DNA-protein complex or by increased cyclization of DNA fragmen