Stem cells, cell transplantation and liver repopulation
โ Scribed by Michael Oertel; David A. Shafritz
- Book ID
- 116270629
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 893 KB
- Volume
- 1782
- Category
- Article
- ISSN
- 0925-4439
No coin nor oath required. For personal study only.
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## **Although it was proposed almost 60 years ago that the adult mammalian liver contains hepatic stem cells, this issue remains controversial. Part of the problem is that no specific marker gene unique to the adult hepatic stem cell has yet been identified, and regeneration of the liver after acu
Liver-directed gene therapy is appropriate for many conditions. Recent work established that liver repopulation with transplanted cells can be effective in treating genetic disorders. Although hepatocytes express therapeutic genes with considerable efยฎciency, correction of genetic disorders is const