Stem cell technology and bioceramics: From cell to gene engineering
β Scribed by Ohgushi, Hajime ;Caplan, Arnold I.
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 901 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0021-9304
No coin nor oath required. For personal study only.
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The increase of adipose tissue mass that accompanies obesity is due both to an increase in adipocyte number (hyperplasia) and size (hypertrophy) (Shepherd et al., 1993) (Fig. 1). Hyperplasia results from the recruitment of preadipose cells from a population of pluripotent stem cells that reside in t
## Abstract Mouse embryonic stem cell lines offer an attractive route for introducing rare genetic alternations into the gene pool since the cells can be preβscreened in culture and the mutations then transmitted into the germline through chimera production. Two applications of this technique seem