Homing of hematopoietic stem cells (HSC) may be defined as the cells' ability to seek marrow stroma selectively, to interact with it and subsequently to lodge within it to initiate hematopoiesis. This complex process is no doubt mediated through multiple recognition/adhesion events. Homing may proce
Stem Cell Homing: Rolling, Crawling, and Nesting
β Scribed by Peter J. Quesenberry and Pamela S. Becker
- Book ID
- 123641624
- Publisher
- National Academy of Sciences
- Year
- 1998
- Tongue
- English
- Weight
- 607 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/46344
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Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for th