6 LASERS IN STEM CELL ACTIVATION, HOMING AND DIFFERENTIATION
β Scribed by L.V. Gasparyan; A.M. Makela; G.E. Brill
- Book ID
- 119625126
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 49 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1572-1000
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The hematopoietic stem cell (HSC) is an attractive target for gene therapy of genetic diseases of the immune and hematopoietic system, and for drug-resistance strategies in which genes conferring resistance to a variety of chemotherapeutic agents can be transduced. Stem cells are relatively easy to
## Abstract Stem cell homing has been studied in syngeneic models and appears to be rapid (<1 h) and dependent on cellular adhesion and migration factors. We utilized a full H2βmismatched transplantation model to determine the basics of allogeneic homing. C57BL/6J LinβScaβ1+ cells were labeled with