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Stem Cell-based Therapy for Neurodegenerative Diseases

✍ Scribed by Fabin Han, Pengzhe (Paul) Lu

Publisher
Springer Singapore;Springer
Year
2020
Tongue
English
Leaves
144
Series
Advances in Experimental Medicine and Biology 1266
Edition
1st ed.
Category
Library
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✦ Synopsis

This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.

✦ Table of Contents

Front Matter ....Pages i-v
Introduction for Stem Cell–Based Therapy for Neurodegenerative Diseases (Fabin Han, Paul Lu)....Pages 1-8
Quality Standards of Stem Cell Sources for Clinical Treatment of Neurodegenerative Diseases (Fabin Han, Yongquan Gu, Hui Zhao, Lin Chen)....Pages 9-19
Stem Cell Therapy for Parkinson’s Disease (Fabin Han, Baoyang Hu)....Pages 21-38
Stem Cell Therapy for Alzheimer’s Disease (Fabin Han, Jianzhong Bi, Liyan Qiao, Ottavio Arancio)....Pages 39-55
Cell Replacement Therapy for Huntington’s Disease (Ruth Monk, Bronwen Connor)....Pages 57-69
Stem Cell Transplantation for Amyotrophic Lateral Sclerosis (Qiang Zhu, Paul Lu)....Pages 71-97
Stem Cells Therapy for Multiple Sclerosis (Nassim Abi Chahine, Paul Lu)....Pages 99-115
Cell-Based Therapy for Spinal Muscular Atrophy (Fabin Han, Somayeh Ebrahimi-Barough, Reyhaneh Abolghasemi, Jafar Ai, Yanming Liu)....Pages 117-125
Stem Cell Transplantation Therapy for Retinal Degenerative Diseases (Fabin Han, Guotong Xu)....Pages 127-139
Future Challenges and Perspectives for Stem Cell Therapy of Neurodegenerative Diseases (Fabin Han, Paul Lu)....Pages 141-145

✦ Subjects

Life Sciences; Stem Cells; Neurosciences; Neurology

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