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Steady state pharmacokinetic profile of indomethacin in elderly patients and young volunteers

โœ Scribed by J. C. McElnay; A. P. Passmore; V. L. S. Crawford; J. G. McConnell; I. C. Taylor; F. S. Walker

Publisher
Springer
Year
1992
Tongue
English
Weight
547 KB
Volume
43
Category
Article
ISSN
0031-6970

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Steady state pharmacokinetics of hydrolysed bopindolol in young and elderly men
โœ D. Holmes; E. Nuesch; J. M. Houle; J. Rosenthaler ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 535 KB

Steady-state pharmacokinetic parameters of the new, long-acting beta-adrenoceptor blocker bopindolol have been measured in 17 young and 20 elderly healthy men. The t 1/2 beta and the AUC(0----24 h) of hydrolysed bopindolol (the active metabolite) were both increased (40% and 26%, respectively) in th