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Steady-State Kinetics and Inhibitor Binding of 3-Deoxy- d - arabino -heptulosonate-7-phosphate Synthase (Tryptophan sensitive) from Escherichia coli †

✍ Scribed by Akowski, James P.; Bauerle, Ronald

Book ID: 126222921
Publisher: American Chemical Society
Year: 1997
Tongue: English
Weight: 149 KB
Volume: 36
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi971135t

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## Abstract In __Escherichia coli__, the phenylalanine‐sensitive 3‐deoxy‐D‐arabino‐heptulosonate‐7‐phosphate synthase (DAHPS) AroG catalyzes the first committed step in the biosynthesis of aromatic compounds. To investigate the feedback inhibition site of AroG, mutated enzymes prepared with sequenc