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Steady state free precession magnetization transfer imaging

✍ Scribed by Oliver Bieri; Tallas C. Mamisch; Siegfried Trattnig; Klaus Scheffler

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
647 KB
Volume
60
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

The formerly proposed concept for magnetization transfer imaging (MTI) using balanced steady‐state free precession (SSFP) image acquisitions is in this work extended to nonbalanced protocols. This allows SSFP‐based MTI of targets with high susceptibility variation (such as the musculoskeletal system), or at ultra‐high magnetic fields (where balanced SSFP suffers from considerable off‐resonance related image degradations). In the first part, SSFP‐based MTI in human brain is analyzed based on magnetization transfer ratio (MTR) histograms. High correlations are observed among all different SSFP MTI protocols and thereby ensure proper conceptual extension to nonbalanced SSFP. The second part demonstrates SSFP‐based MTI allowing fast acquisition of high resolution volumetric MTR data from human brain and cartilage at low (1.5T) to ultra‐high (7.0T) magnetic fields. Magn Reson Med 60:1261–1266, 2008. © 2008 Wiley‐Liss, Inc.

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