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Steady-state cerebrospinal fluid transfer of verapamil and metabolites in patients with schizophrenia

✍ Scribed by Narang, P K; Blumhardt, C L; Doran, A R; Pickar, D

Book ID
109844411
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
617 KB
Volume
44
Category
Article
ISSN
0009-9236

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The concentrations of chlorpromazine and some of its metabolites in blood plasma and CSF from chlorpromazine-treated schizophrenics with different therapeutic results were studied. Compared to a good responder a poor responder showed very high levels of the inactive metabolite chlorpromazine sulphox