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Cerebrospinal fluid levels of chlorpromazine and its metabolites in schizophrenia

✍ Scribed by S. Axelsson; S. Jönsson; L. Nordgren

Publisher
Springer-Verlag
Year
1975
Tongue
English
Weight
211 KB
Volume
221
Category
Article
ISSN
1433-8491

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✦ Synopsis

The concentrations of chlorpromazine and some of its metabolites in blood plasma and CSF from chlorpromazine-treated schizophrenics with different therapeutic results were studied. Compared to a good responder a poor responder showed very high levels of the inactive metabolite chlorpromazine sulphoxide in the CSF.

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