𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stavudine + didanosine effective anti-HIV therapy

Book ID
120877661
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
1997
Weight
149 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Effect of temperature on the high-perfor
Effect of temperature on the high-performance liquid chromatographic separation of the anti-HIV agents, didanosine and stavudine
✍ Frank A. Stancato; Nuggehally R. Srinivas; Catherine A. Knupp πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 204 KB πŸ‘ 2 views

This paper examines the effect of temperature on the chromatographic separation characteristics of anti-HIV agents, didanosine and stavudine. As a result of lowering the column temperature, an improved resolution between didanosine and stavudine peaks is observed. Thus, lower temperatures may permit

Depletion of mitochondrial DNA in liver
Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine
✍ Ulrich A. Walker; Jochen BΓ€uerle; Montse Laguno; Javier Murillas; Stefan Mauss; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 161 KB

The "D drug" HIV reverse-transcriptase inhibitors zalcitabine, didanosine, and stavudine are relatively strong inhibitors of polymerase-gamma compared with the "non-D drugs" zidovudine, lamivudine, and abacavir. D drugs deplete mitochondrial DNA (mtDNA) in cultured hepatocytes. This mtDNA depletion